Classifications for the General Surgery Clinic
What you'll be asked across the desk, and what each one actually changes.
Clinic is where classifications earn their keep. A grade or stage is shorthand for a decision — which operation, which interval, which conversation with the patient. This reference gives you the system and the consequence.
Last reviewed: August 2026. Guidelines change. Check your trust protocol and current NICE/BSG/ACPGBI/AUGIS guidance before applying anything here to patient care.
PART ONE — CROSS-CUTTING SYSTEMS
These come up in every clinic regardless of subspecialty.
1. TNM — and the 9th Edition Change
The UICC TNM 9th edition took effect on 1 January 2026. Most people are still quoting the 8th. Knowing this is a cheap and reliable way to sound current.
- Major revisions in the 9th edition: head and neck (salivary gland, nasopharyngeal, HPV-related oropharyngeal), lung, thymoma, mesothelioma.
- More limited changes for colorectal, breast and most general surgical cancers — including a revised definition of tumour deposits in colorectal cancer.
- UK cancer registries and MDTs are transitioning; your trust may still be reporting in 8th edition. Say which edition you're using.
TNM prefixes — get these right
| Prefix | Meaning |
|---|---|
| c | Clinical staging (pre-treatment, from examination and imaging) |
| p | Pathological staging (after resection) |
| yp | Pathological staging after neoadjuvant therapy |
| r | Recurrent tumour |
| a | Determined at autopsy |
ypT0N0 after neoadjuvant chemoradiotherapy = pathological complete response. Strong prognostic marker in rectal and oesophageal cancer.
2. ASA Physical Status
| Grade | Definition |
|---|---|
| I | Healthy patient, no systemic disease |
| II | Mild systemic disease, no functional limitation (controlled hypertension, T2DM without end-organ damage, BMI 30–40, smoker, mild asthma, pregnancy) |
| III | Severe systemic disease with functional limitation (poorly controlled diabetes or hypertension, COPD, BMI >40, active hepatitis, alcohol dependence, pacemaker, MI/stroke >3 months ago) |
| IV | Severe systemic disease that is a constant threat to life (MI <3 months, severe heart failure, ongoing ischaemia, sepsis, DIC) |
| V | Moribund, not expected to survive without the operation (ruptured AAA, massive PE, intracranial bleed with herniation) |
| VI | Brain-dead organ donor |
Add E for emergency: ASA IIIE.
ASA is about the patient, not the operation. Combine with procedure-specific risk and functional capacity.
3. Performance Status (ECOG / WHO)
Determines fitness for oncological treatment. Comes up in every cancer clinic and MDT.
| Grade | Description |
|---|---|
| 0 | Fully active, no restriction |
| 1 | Restricted in strenuous activity, ambulatory, able to do light work |
| 2 | Ambulatory, self-caring, unable to work, up and about >50% of waking hours |
| 3 | Limited self-care, confined to bed or chair >50% of waking hours |
| 4 | Completely disabled, no self-care, totally confined to bed or chair |
| 5 | Dead |
PS 0–1 — candidates for radical treatment and most chemotherapy. PS 2 — the grey zone; treatment often modified. PS 3–4 — generally best supportive care or palliative intent only.
The practical bedside question that separates 1 from 2: "Are you up and dressed for most of the day?"
4. Clavien-Dindo — Post-operative Complications
The standard for grading complications in audit, research and consent discussions.
| Grade | Definition |
|---|---|
| I | Any deviation from normal post-op course not requiring pharmacological (beyond antiemetics, antipyretics, analgesics, diuretics, electrolytes), surgical, endoscopic or radiological intervention. Includes wound infection opened at bedside |
| II | Requiring pharmacological treatment beyond grade I — includes blood transfusion and total parenteral nutrition |
| IIIa | Requiring intervention not under general anaesthetic (e.g. radiologically guided drain) |
| IIIb | Requiring intervention under general anaesthetic (return to theatre) |
| IVa | Single-organ dysfunction requiring ICU/HDU |
| IVb | Multi-organ dysfunction requiring ICU/HDU |
| V | Death |
Suffix "d" if the patient has a persisting disability at discharge.
The Comprehensive Complication Index (CCI) aggregates all complications in a single patient into a 0–100 score — increasingly used in trials because Clavien-Dindo only captures the most severe event.
5. Risk Scores
- P-POSSUM — Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity. Twelve physiological and six operative variables. Widely used but overestimates mortality in low-risk patients.
- NELA risk calculator — the standard for emergency laparotomy in the UK. NELA mandates that a documented risk assessment is made pre-operatively. Predicted mortality ≥5% should trigger consultant surgeon and consultant anaesthetist presence and consideration of critical care.
- SORT (Surgical Outcome Risk Tool) — quick pre-operative estimate for elective surgery.
Documenting a numerical risk estimate in the consent discussion is both good practice and exactly what Montgomery requires.
PART TWO — BREAST CLINIC
6. Triple Assessment Coding
Every breast clinic letter uses these. Each modality is scored 1–5 on the same logic: 1 = inadequate/normal, 5 = malignant.
| Score | Clinical (P) | Imaging (U ultrasound / M mammogram) | Core biopsy (B) | Cytology (C) |
|---|---|---|---|---|
| 1 | Normal | Normal | Normal tissue | Inadequate |
| 2 | Benign | Benign | Benign | Benign |
| 3 | Probably benign / uncertain | Probably benign | Atypia, probably benign | Atypia, probably benign |
| 4 | Suspicious | Suspicious | Suspicious of malignancy | Suspicious |
| 5 | Malignant | Malignant | Malignant | Malignant |
B5 is subdivided: B5a = carcinoma in situ; B5b = invasive carcinoma. This distinction matters — B5a may not need axillary staging.
What the discordant results mean
- Triple assessment is concordant or it isn't. A P2 U2 B5 is discordant and the biopsy wins. A P4 U2 B2 is discordant and needs re-biopsy or excision — do not reassure on the strength of the two benign results.
- B3 is the difficult one — atypia of uncertain malignant potential. Includes atypical ductal hyperplasia, lobular neoplasia, papillary lesions, radial scar, phyllodes. Managed by vacuum-assisted excision or diagnostic excision, discussed at MDT. Upgrade rate to malignancy is meaningful.
- C3–C5 cytology should generally be followed by core biopsy — cytology cannot distinguish invasive from in situ disease.
7. Nottingham Grade (modified Bloom-Richardson / Scarff-Bloom-Richardson)
Three components, each scored 1–3:
- Tubule formation (>75% / 10–75% / <10%)
- Nuclear pleomorphism (small uniform / moderate variation / marked variation)
- Mitotic count (per 10 high-power fields, field-area adjusted)
Total 3–9:
| Total | Grade |
|---|---|
| 3–5 | Grade 1 — well differentiated |
| 6–7 | Grade 2 — moderately differentiated |
| 8–9 | Grade 3 — poorly differentiated |
8. Nottingham Prognostic Index (NPI)
NPI = (0.2 × tumour size in cm) + lymph node stage (1–3) + grade (1–3)
Node stage: 1 = node negative; 2 = 1–3 nodes; 3 = ≥4 nodes.
| NPI | Prognostic group | Approximate 10-year survival |
|---|---|---|
| ≤2.4 | Excellent | ~95% |
| 2.41–3.4 | Good | ~85% |
| 3.41–4.4 | Moderate I | ~70% |
| 4.41–5.4 | Moderate II | ~50% |
| >5.4 | Poor | ~20% |
Still quoted in UK breast MDTs, though PREDICT (the online tool incorporating age, ER, HER2, Ki67 and treatment modality) has largely superseded it for counselling patients about the benefit of adjuvant therapy.
9. Receptor Status — the three that determine treatment
| Receptor | Threshold | Consequence |
|---|---|---|
| ER | Allred score, or ≥1% nuclear staining | Endocrine therapy (AI post-menopausal, tamoxifen pre-menopausal) |
| PR | As ER | Prognostic; supports ER positivity |
| HER2 | IHC 3+ = positive; IHC 2+ = equivocal → ISH/FISH; 0–1+ negative | Trastuzumab ± pertuzumab |
Triple negative (ER−, PR−, HER2−) — no targeted therapy available, chemotherapy is the mainstay, associated with BRCA1 and worse prognosis.
HER2-low (IHC 1+, or 2+ with negative ISH) is now a recognised category with implications for antibody-drug conjugates — worth knowing that the binary has softened.
10. Breast Surgical Margins and Axillary Staging
- Invasive cancer: "no ink on tumour" is the internationally accepted margin; UK practice commonly uses ≥1 mm. NICE supports 1 mm.
- DCIS: ≥2 mm is the widely accepted standard.
- Sentinel lymph node biopsy for clinically and radiologically node-negative axilla.
- Positive SLNB with 1–2 macrometastases in a patient having breast conservation and whole-breast radiotherapy — axillary radiotherapy is equivalent to clearance (AMAROS), and completion clearance may be omitted altogether (Z0011).
- Isolated tumour cells (≤0.2 mm) and micrometastases (0.2–2 mm) generally do not mandate further axillary surgery.
PART THREE — COLORECTAL CLINIC
11. Hinchey Classification — Perforated Diverticulitis
The original is an operative/CT classification, but you will be asked in clinic when discussing interval management.
| Stage | Finding | Typical management |
|---|---|---|
| I | Pericolic abscess or phlegmon confined to mesentery | Antibiotics; drain if >3–4 cm |
| II | Pelvic, intra-abdominal or retroperitoneal abscess | Radiologically guided drainage + antibiotics |
| III | Generalised purulent peritonitis | Surgery — Hartmann's, resection with anastomosis ± defunctioning, or laparoscopic lavage (controversial) |
| IV | Generalised faeculent peritonitis | Surgery — Hartmann's |
Modified Hinchey adds 0 (mild clinical diverticulitis) and subdivides Ia (confined pericolic inflammation) from Ib (pericolic abscess).
What it changes in clinic
- Uncomplicated diverticulitis — NICE supports no antibiotics in selected systemically well, immunocompetent patients without significant comorbidity. This surprises people.
- Routine interval colonoscopy after an episode of uncomplicated diverticulitis is no longer recommended — but is indicated after complicated diverticulitis (abscess, perforation) to exclude an underlying malignancy, usually at 6–8 weeks.
- Elective sigmoid colectomy is not indicated purely on the basis of number of attacks. Decide on the basis of ongoing symptoms, complications (stricture, fistula), immunosuppression and patient preference.
12. Colorectal Cancer — TNM and Dukes
TNM (essentials)
| Tis | Carcinoma in situ / intramucosal (confined by muscularis mucosae) |
| T1 | Invades submucosa |
| T2 | Invades muscularis propria |
| T3 | Through muscularis propria into pericolorectal tissues |
| T4a | Penetrates visceral peritoneum |
| T4b | Directly invades adjacent organs or structures |
| N0 | No regional nodes |
| N1a/b/c | 1 node / 2–3 nodes / tumour deposits without nodal involvement |
| N2a/b | 4–6 nodes / ≥7 nodes |
| M1a/b/c | One organ / more than one organ / peritoneal metastasis |
A minimum of 12 lymph nodes should be examined for adequate staging. Fewer than 12 is a quality flag and may prompt upstaging of management.
Dukes (historical but still quoted)
| Dukes | Equivalent |
|---|---|
| A | Confined to bowel wall (T1–T2 N0) |
| B | Through bowel wall, nodes negative (T3–T4 N0) |
| C | Nodes positive (any T, N1–N2) |
| D | Distant metastases (added later, not in Dukes' original) |
Dukes never included stage D. If a consultant asks, that's usually the point they're testing.
13. Rectal Cancer — MRI Staging
The single most important staging investigation in rectal cancer, and what the MDT actually discusses.
The three things the radiologist reports
-
T stage — with T3 subdivided by depth of extramural spread:
- T3a <1 mm
- T3b 1–5 mm
- T3c 5–15 mm
- T3d >15 mm
-
CRM (circumferential resection margin) — distance from tumour (or involved node or deposit) to the mesorectal fascia. Threatened or involved if ≤1 mm. This is the strongest predictor of local recurrence and the main determinant of neoadjuvant therapy.
-
EMVI (extramural venous invasion) — independent predictor of distant recurrence. EMVI-positive disease is treated more aggressively.
Height matters
- Low rectal tumours (<5 cm from anal verge) — risk to the sphincter complex; may need APER or intersphincteric resection.
- Mid (5–10 cm) and high (10–15 cm) — anterior resection with TME.
What drives neoadjuvant treatment
- Threatened CRM, T4, low tumours, EMVI positive, N2 → neoadjuvant long-course chemoradiotherapy.
- Short-course radiotherapy for downstaging in selected cases.
- Total neoadjuvant therapy (TNT) — chemoradiotherapy plus systemic chemotherapy before surgery — improves distant control and increases complete response rates.
- Watch and wait for clinical complete response after chemoradiotherapy is now an established option in specialist centres with rigorous surveillance.
14. Parks Classification — Fistula-in-Ano
Defined by the relationship of the primary tract to the external anal sphincter.
| Type | Course | Frequency |
|---|---|---|
| Intersphincteric | Between internal and external sphincter, in the intersphincteric plane | ~70% |
| Transsphincteric | Crosses the external sphincter into the ischioanal fossa | ~25% |
| Suprasphincteric | Up over the puborectalis, then down through the levators | ~5% |
| Extrasphincteric | From perineum through levators into rectum, bypassing the sphincter entirely | ~1% |
What it changes
- Low fistulae (minimal external sphincter involvement) → fistulotomy, high success rate.
- High fistulae (significant sphincter involvement, anterior fistula in a woman, pre-existing incontinence, Crohn's) → sphincter-preserving approach: loose seton, LIFT (ligation of intersphincteric fistula tract), advancement flap, or fistula plug.
- Extrasphincteric fistulae are usually secondary — think Crohn's, malignancy, trauma, diverticular disease, or iatrogenic. Investigate the cause.
- MRI pelvis is the imaging modality of choice for complex, recurrent, or Crohn's-related disease.
- Always ask about continence before operating, and document it. This is the commonest source of litigation in benign anorectal surgery.
Goodsall's rule predicts the internal opening: anterior external openings track radially; posterior openings curve to the posterior midline. Less reliable anteriorly, in recurrent fistulae, and in Crohn's.
15. Faecal Incontinence Scoring
St Mark's (Vaizey) score — 0–24
Seven items: incontinence to solid / liquid / gas, alteration of lifestyle (each 0–4 by frequency), plus need to wear a pad, use of constipating medication, and lack of ability to defer defaecation for 15 minutes (each 0 or 2–4).
0 = perfect continence; 24 = completely incontinent.
Wexner (Cleveland Clinic) score — 0–20
The same first five frequency items without the deferral and medication weighting. Simpler, widely used.
Both are worth using in clinic because they quantify change after treatment — essential for audit, and for a meaningful conversation with the patient about whether an intervention worked.
16. Oxford Rectal Prolapse Grading (defaecating proctography)
| Grade | Finding |
|---|---|
| I | High rectal intussusception (above the rectocele) |
| II | Low rectal intussusception |
| III | High rectoanal intussusception (into anal canal) |
| IV | Low rectoanal intussusception |
| V | Overt external rectal prolapse |
Grades III–V correlate with symptoms; I–II are common in asymptomatic people and should not by themselves prompt surgery.
17. Bristol Stool Chart
Deceptively useful — it converts a vague history into something you can track.
| Type | Description | Interpretation |
|---|---|---|
| 1 | Separate hard lumps, like nuts | Severe constipation |
| 2 | Sausage-shaped, lumpy | Mild constipation |
| 3 | Sausage with cracks on surface | Normal |
| 4 | Smooth, soft sausage or snake | Normal (ideal) |
| 5 | Soft blobs with clear-cut edges | Lacking fibre |
| 6 | Mushy, fluffy pieces, ragged edges | Mild diarrhoea |
| 7 | Entirely liquid, no solid pieces | Severe diarrhoea |
18. Goligher — Haemorrhoids
| Grade | Description | Typical management |
|---|---|---|
| I | Bleed, do not prolapse | Conservative: fibre, fluids, topical |
| II | Prolapse on straining, reduce spontaneously | Rubber band ligation |
| III | Prolapse, require manual reduction | Banding, HALO/THD, haemorrhoidectomy |
| IV | Irreducible | Haemorrhoidectomy |
Exclude a proximal source before attributing rectal bleeding to haemorrhoids — particularly with altered bowel habit, iron deficiency anaemia, age >40, or family history. Haemorrhoids are common; so is coexisting colorectal cancer.
PART FOUR — HPB AND UPPER GI CLINIC
19. Tokyo Guidelines 2018 (TG18) — Acute Cholecystitis Severity
| Grade | Definition |
|---|---|
| Grade I (mild) | Acute cholecystitis in a healthy patient with no organ dysfunction and only mild inflammatory change in the gallbladder |
| Grade II (moderate) | Any one of: WCC >18 × 10⁹/L; palpable tender mass in RUQ; duration >72 hours; marked local inflammation (gangrenous or emphysematous cholecystitis, pericholecystic or hepatic abscess, biliary peritonitis) |
| Grade III (severe) | Associated with organ dysfunction — cardiovascular (needing vasopressors), neurological, respiratory (P/F <300), renal (creatinine >176 µmol/L or oliguria), hepatic (INR >1.5), haematological (platelets <100) |
What it changes
- Grade I and II — early laparoscopic cholecystectomy where local expertise allows. NICE CG188 recommends surgery within 7 days of symptom onset, during the index admission.
- Grade III — resuscitate and treat organ failure; percutaneous cholecystostomy if not fit for surgery; delayed cholecystectomy once recovered. Some units with appropriate expertise still operate early in selected Grade III patients.
- Charlson Comorbidity Index and ASA are incorporated in TG18 to identify Grade III patients who might still tolerate early surgery.
20. Tokyo Guidelines 2018 — Acute Cholangitis
Diagnosis requires elements from all three of:
- A. Systemic inflammation — fever/rigors or raised inflammatory markers
- B. Cholestasis — jaundice or abnormal LFTs
- C. Imaging — biliary dilatation or evidence of an aetiology (stone, stricture, stent)
Suspected = one item from A plus one from B or C. Definite = one item from each.
| Grade | Definition | Timing of drainage |
|---|---|---|
| I (mild) | Responds to initial medical management | Drainage if no response to antibiotics |
| II (moderate) | Any 2 of: WCC >12 or <4; fever ≥39°C; age ≥75; bilirubin ≥85 µmol/L; albumin low | Early biliary drainage |
| III (severe) | Organ dysfunction (as for cholecystitis) | Urgent biliary drainage |
Charcot's triad (RUQ pain, fever, jaundice) is present in only around 50–70%. Reynolds' pentad adds hypotension and confusion — that is Grade III until proven otherwise.
Drainage: ERCP first-line; PTC if ERCP fails or anatomy prevents it; surgical drainage now rare.
21. Revised Atlanta Classification (2012) — Acute Pancreatitis
Diagnosis — 2 of 3
- Characteristic abdominal pain
- Amylase or lipase >3× upper limit of normal
- Characteristic imaging findings
Severity
| Grade | Definition |
|---|---|
| Mild | No organ failure, no local or systemic complications |
| Moderately severe | Transient organ failure (<48 h) and/or local or systemic complications |
| Severe | Persistent organ failure (>48 h), single or multiple |
Organ failure defined by modified Marshall score ≥2 for respiratory, cardiovascular or renal systems.
Local complications — the terminology matters
| Timing | Non-necrotising | Necrotising |
|---|---|---|
| <4 weeks | Acute peripancreatic fluid collection (APFC) | Acute necrotic collection (ANC) |
| >4 weeks | Pseudocyst (encapsulated, no solid content) | Walled-off necrosis (WON) |
Getting this right matters because it dictates intervention: a pseudocyst is drained endoscopically if symptomatic; walled-off necrosis requires a step-up approach (percutaneous or endoscopic drainage first, then minimally invasive necrosectomy only if needed) rather than open necrosectomy.
Phases
- Early (first week) — driven by SIRS and organ failure. Severity determined by organ failure, not by CT findings. CT in the first 72 hours underestimates necrosis — don't scan too early unless the diagnosis is in doubt.
- Late (>1 week) — driven by local complications and persistent organ failure.
Glasgow-Imrie (PANCREAS) and CRP >150 at 48 hours remain the practical UK severity predictors.
22. Strasberg Classification — Bile Duct Injury
The classification to know if you are operating on gallbladders.
| Type | Injury |
|---|---|
| A | Leak from cystic duct stump or minor duct in the liver bed (duct of Luschka) |
| B | Occlusion of an aberrant right hepatic duct |
| C | Transection without ligation of an aberrant right hepatic duct |
| D | Lateral injury to a major bile duct |
| E1–E5 | Circumferential injury (Bismuth classification) — E1 >2 cm from confluence; E2 <2 cm; E3 at confluence; E4 destroys confluence; E5 involves aberrant right duct + common duct |
What it changes
- Type A — most common, usually managed by ERCP and stenting ± drainage of collection.
- Types B and C — depend on the volume of liver drained; may need reconstruction or, occasionally, resection.
- Types D and E — do not attempt repair yourself. Control sepsis, drain, image (MRCP + CT), and refer to a specialist HPB centre. Repair by the injuring surgeon is associated with substantially worse outcomes. Reconstruction is usually Roux-en-Y hepaticojejunostomy.
Prevention beats classification: the critical view of safety, and a willingness to perform subtotal cholecystectomy rather than persist with unclear anatomy.
23. Bismuth-Corlette — Hilar Cholangiocarcinoma (Klatskin Tumour)
| Type | Extent | Typical resection |
|---|---|---|
| I | Below the confluence, common hepatic duct only | Bile duct resection ± hepatectomy |
| II | Reaches the confluence | Bile duct resection + caudate lobectomy |
| IIIa | Confluence + right hepatic duct | Right hepatectomy + caudate |
| IIIb | Confluence + left hepatic duct | Left hepatectomy + caudate |
| IV | Both right and left hepatic ducts, or multifocal | Often unresectable; extended hepatectomy or transplant protocol in selected cases |
Caudate lobe resection is routinely included because the caudate ducts drain directly into the confluence.
Assessment for resectability requires future liver remnant estimation and often portal vein embolisation to hypertrophy the remnant.
24. Mirizzi Syndrome — Csendes Classification
Extrinsic compression of the common hepatic duct by a stone impacted in Hartmann's pouch or the cystic duct.
| Type | Finding |
|---|---|
| I | External compression only, no fistula |
| II | Cholecystobiliary fistula involving <1/3 of the duct circumference |
| III | Fistula involving up to 2/3 of the circumference |
| IV | Complete destruction of the bile duct wall |
| V | Any of the above plus a cholecystoenteric fistula (Va without, Vb with gallstone ileus) |
Type I may be managed laparoscopically with care (though conversion rates are high). Types II–IV generally need open surgery with biliary reconstruction. Mirizzi is associated with gallbladder cancer in around 5–28% — send the specimen and consider the diagnosis.
25. Child-Pugh and MELD
Child-Pugh — operative risk in cirrhosis
| Parameter | 1 point | 2 points | 3 points |
|---|---|---|---|
| Bilirubin (µmol/L) | <34 | 34–50 | >50 |
| Albumin (g/L) | >35 | 28–35 | <28 |
| INR | <1.7 | 1.7–2.3 | >2.3 |
| Ascites | None | Mild | Moderate–severe |
| Encephalopathy | None | Grade 1–2 | Grade 3–4 |
| Class | Score | Approximate operative mortality (major abdominal surgery) |
|---|---|---|
| A | 5–6 | ~10% |
| B | 7–9 | ~30% |
| C | 10–15 | >70–80% |
Child-Pugh C is a contraindication to elective major abdominal surgery.
MELD
Uses bilirubin, INR and creatinine (MELD-Na adds sodium). Used for transplant allocation and increasingly for perioperative risk. MELD >15 predicts significantly increased surgical mortality.
PART FIVE — HERNIA CLINIC
26. EHS Classification — Groin Hernia
The European Hernia Society system, designed to be recorded intraoperatively in a grid.
Type:
- L — Lateral (indirect)
- M — Medial (direct)
- F — Femoral
Size (using the index finger or a 1.5 cm jaw of a laparoscopic grasper as the reference):
- 0 — no hernia detectable
- 1 — <1.5 cm (one finger)
- 2 — 1.5–3 cm (two fingers)
- 3 — >3 cm (more than two fingers)
P = primary, R = recurrent.
Recorded as, for example, L2 P — a primary indirect hernia with a 1.5–3 cm defect.
The older Nyhus classification (still quoted)
| Type | Description |
|---|---|
| I | Indirect, normal internal ring (paediatric) |
| II | Indirect, dilated internal ring, posterior wall intact |
| IIIa | Direct |
| IIIb | Indirect with posterior wall defect (pantaloon, sliding, massive) |
| IIIc | Femoral |
| IV | Recurrent (a direct, b indirect, c femoral, d combined) |
What matters in clinic
- Femoral hernias — repair even if asymptomatic. High strangulation risk. More common in women, though inguinal hernia remains the commonest hernia in women.
- Asymptomatic or minimally symptomatic inguinal hernia in men — watchful waiting is a legitimate option, though most eventually cross over to surgery.
- Bilateral or recurrent hernias — laparoscopic repair (TEP or TAPP) is favoured.
- Chronic post-herniorrhaphy pain affects around 10% and is the most important thing to consent for. Document it.
27. EHS Classification — Ventral and Incisional Hernia
Midline (M):
| Zone | Location |
|---|---|
| M1 | Subxiphoidal (to 3 cm below xiphoid) |
| M2 | Epigastric |
| M3 | Umbilical |
| M4 | Infraumbilical |
| M5 | Suprapubic (to 3 cm above pubis) |
Lateral (L): L1 subcostal, L2 flank, L3 iliac, L4 lumbar.
Width (W): W1 <4 cm; W2 4–10 cm; W3 ≥10 cm.
W3 hernias and those with loss of domain need specialist assessment — component separation, botulinum toxin to the lateral abdominal wall, or preoperative progressive pneumoperitoneum.
PART SIX — SKIN AND SOFT TISSUE
28. Melanoma — Breslow Thickness and Excision Margins
Breslow thickness (mm, measured from the granular layer of the epidermis to the deepest tumour cell) is the single most important prognostic factor.
| Breslow | T stage | Recommended wide local excision margin |
|---|---|---|
| In situ | Tis | 0.5 cm |
| ≤1.0 mm | T1 | 1 cm |
| 1.01–2.0 mm | T2 | 1–2 cm |
| 2.01–4.0 mm | T3 | 2 cm |
| >4.0 mm | T4 | 2 cm |
Each T stage is subdivided a (no ulceration) and b (ulceration present). Ulceration upstages and independently worsens prognosis.
Clark levels (I–V, by anatomical layer) are historical and no longer used for staging — mention only if asked.
Sentinel node biopsy
- Offered for Breslow >0.8 mm, or ≤0.8 mm with ulceration.
- Staging, not therapeutic — MSLT-II showed no overall survival benefit from completion lymphadenectomy after a positive SLNB, but it identifies patients for adjuvant immunotherapy or targeted therapy.
- BRAF V600 testing in stage III–IV disease (approximately 50% of cutaneous melanomas) — determines eligibility for dabrafenib/trametinib.
29. Non-Melanoma Skin Cancer — Risk Stratification
Basal cell carcinoma
Low risk: <20 mm on trunk/extremities, nodular or superficial subtype, primary, immunocompetent patient. High risk: H-zone of the face (periorbital, nose, lips, ears, nasolabial fold), >20 mm, morphoeic/infiltrative/micronodular subtype, recurrent, perineural invasion, immunosuppression.
Margins: 4–5 mm for low-risk lesions. Mohs micrographic surgery for high-risk sites, recurrent lesions, and aggressive subtypes.
Incomplete excision → re-excise. Recurrence rate after incomplete excision is 30–40%, and recurrent BCCs are considerably harder to treat.
Squamous cell carcinoma
High-risk features: >20 mm diameter, >4 mm depth, poorly differentiated, perineural or lymphovascular invasion, ear/lip/temple location, recurrent, immunosuppression (particularly transplant recipients), arising in scar or chronic wound.
Margins: 4 mm low risk; 6 mm or more for high-risk lesions. Consider imaging and MDT for high-risk disease — SCC does metastasise (2–5% overall, higher with risk features).
PART SEVEN — THYROID AND NECK CLINIC
30. Thyroid Nodule — U and Thy Classifications
Ultrasound (BTA U classification)
| Grade | Interpretation | Action |
|---|---|---|
| U1 | Normal | — |
| U2 | Benign | Reassure and discharge |
| U3 | Indeterminate / equivocal | FNA |
| U4 | Suspicious | FNA |
| U5 | Malignant | FNA |
Suspicious features: solid hypoechoic, microcalcification, taller-than-wide shape, irregular or lobulated margins, intranodular vascularity, associated abnormal lymph nodes.
Cytology (RCPath Thy classification)
| Grade | Meaning | Action |
|---|---|---|
| Thy1 | Non-diagnostic (Thy1c = cystic) | Repeat FNA |
| Thy2 | Benign (Thy2c = cystic) | Discharge or interval USS |
| Thy3a | Atypia of undetermined significance | Repeat FNA or diagnostic lobectomy |
| Thy3f | Follicular neoplasm | Diagnostic hemithyroidectomy |
| Thy4 | Suspicious of malignancy | Hemithyroidectomy or total thyroidectomy |
| Thy5 | Malignant | Definitive surgery |
The key concept
Thy3f requires surgery because cytology cannot distinguish follicular adenoma from follicular carcinoma. The distinction rests entirely on capsular or vascular invasion, which requires examination of the whole capsule on histology — a needle cannot answer it. Roughly 20% of Thy3f lesions turn out malignant.
The US equivalent is the Bethesda system (I–VI); ACR TI-RADS is the US ultrasound scoring system. Know that they exist and map roughly onto Thy/U.
31. Thyroid Cancer — Surgical Extent
| Situation | Operation |
|---|---|
| Papillary <1 cm (microcarcinoma), no adverse features | Lobectomy (or active surveillance in selected cases) |
| Papillary 1–4 cm, no extrathyroidal extension or nodal disease | Lobectomy or total thyroidectomy |
| Papillary >4 cm, extrathyroidal extension, nodal disease, prior radiation | Total thyroidectomy |
| Medullary | Total thyroidectomy + central compartment (level VI) dissection |
| Anaplastic | Rarely resectable; urgent MDT, airway assessment |
Before any medullary thyroid cancer surgery: test for RET mutation and exclude phaeochromocytoma (MEN2A/2B). An unsuspected phaeochromocytoma under anaesthesia is potentially fatal.
Consent for thyroidectomy must include: recurrent laryngeal nerve injury (voice), external branch of superior laryngeal nerve (pitch), hypoparathyroidism, and haematoma with airway compromise — with clip removers at the bedside.
PART EIGHT — VASCULAR (WHAT A GENERAL SURGEON STILL SEES)
32. Fontaine and Rutherford — Peripheral Arterial Disease
| Fontaine | Rutherford | Clinical |
|---|---|---|
| I | 0 | Asymptomatic |
| IIa | 1 | Mild claudication (>200 m) |
| IIb | 2–3 | Moderate–severe claudication (<200 m) |
| III | 4 | Ischaemic rest pain |
| IV | 5–6 | Ulceration or gangrene |
Fontaine III–IV = chronic limb-threatening ischaemia (CLTI) → urgent vascular referral for revascularisation.
ABPI: >1.4 falsely elevated (calcification, diabetes); 0.9–1.4 normal; 0.5–0.9 claudication; <0.5 severe; <0.4 critical.
Claudication alone — supervised exercise therapy plus cardiovascular risk factor modification is first-line (NICE). The limb prognosis is good; the cardiovascular prognosis is not.
33. WIfI Classification — Diabetic and Ischaemic Foot
Three components, each graded 0–3:
- Wound (extent and depth)
- Ischaemia (ABPI, ankle and toe pressures)
- foot Infection (severity)
Produces a stratified estimate of amputation risk at 1 year and likely benefit from revascularisation. More useful than ABPI alone in diabetics with calcified vessels.
34. CEAP — Chronic Venous Disease
| Class | Finding |
|---|---|
| C0 | No visible venous disease |
| C1 | Telangiectasia / reticular veins |
| C2 | Varicose veins |
| C3 | Oedema |
| C4a / C4b | Pigmentation or eczema / lipodermatosclerosis or atrophie blanche |
| C5 | Healed venous ulcer |
| C6 | Active venous ulcer |
Suffix S (symptomatic) or A (asymptomatic). Full CEAP also records Etiology, Anatomy, Pathophysiology.
C2S and above with confirmed truncal reflux on duplex → refer for intervention. NICE NG168 recommends endovenous thermal ablation first-line, foam sclerotherapy second, surgery third.
C6 (active ulcer) → compression plus early endovenous ablation, which speeds healing and reduces recurrence (EVRA trial).
QUICK REFERENCE — Clinic Cheat Sheet
| Presentation | Classification | The decision it drives |
|---|---|---|
| Breast lump | P / U / M / B / C 1–5 | Concordance; B3 → VAE; B5 → cancer pathway |
| Breast cancer | Nottingham grade, NPI, receptors | Adjuvant therapy; PREDICT for counselling |
| Diverticulitis | Hinchey | II → drainage; III–IV → surgery; complicated → interval scope |
| Rectal cancer | MRI T, CRM, EMVI | CRM ≤1 mm → neoadjuvant chemoradiotherapy |
| Fistula-in-ano | Parks | Low → fistulotomy; high → seton/LIFT/flap |
| Incontinence | St Mark's / Wexner | Quantifies baseline and response |
| Acute cholecystitis | TG18 grade | I–II → early lap chole within 7 days |
| Cholangitis | TG18 grade | II → early drainage; III → urgent ERCP |
| Pancreatitis | Revised Atlanta | Pseudocyst vs WON → different intervention |
| Bile duct injury | Strasberg | D/E → don't repair, refer to HPB centre |
| Cirrhosis | Child-Pugh / MELD | C → no elective major surgery |
| Groin hernia | EHS L/M/F + size | Femoral → always repair |
| Ventral hernia | EHS M/L + W1–3 | W3 or loss of domain → specialist |
| Pigmented lesion | Breslow ± ulceration | Determines excision margin and SLNB |
| Thyroid nodule | U then Thy | Thy3f → diagnostic hemithyroidectomy |
| Claudication | Fontaine / ABPI | III–IV → urgent vascular referral |
| Varicose veins | CEAP | C2S+ with reflux → endovenous ablation |
| Any operation | ASA, ECOG, NELA/P-POSSUM | Fitness, consent, escalation planning |
| Any complication | Clavien-Dindo | Audit, M&M, honest outcome reporting |
Using This in Clinic
Three habits that make classifications work for you rather than against you:
Give the grade and the consequence in the same breath. "Hinchey II, so I'd want radiological drainage rather than theatre" is a complete answer. "Hinchey II" is a quiz response.
Say which version you're using. TNM 8th or 9th. BSG or ESGE intervals. Original or modified Hinchey. Knowing that versions differ is a stronger position than confidently quoting one.
Record the score in the letter. A Vaizey score, a CEAP class, an EHS grade — these make the next clinic letter meaningful and turn your practice into auditable data. It also makes you the registrar whose letters people actually want to read.
This reference reflects guidance current as of August 2026. NICE, BSG, ACPGBI, AUGIS, ABS and Vascular Society guidance is periodically revised — verify against current published guidance and local trust protocol before applying to patient care. Educational resource; not a substitute for clinical judgement.
For educational use only. Always check your local trust protocol and the current guideline position before acting on anything here.